Metagenics – UltraFlora Weight & Metabolic Health with Akkermansia 30 Capsules

Original price was: $79.95.Current price is: $70.99. — available on subscription

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Vegetarian

Clinically Trialled Postbiotic

Fridge Free

Daily Dose

Weight maintenance isn’t willpower. It’s gut power.

Highlights

30 billion clinically trialled postbiotic Akkermansia municiphila (MucT®) cells
Scientifically researched Green Tea
Helps maintain healthy body weight & Body Mass Index.1
Helps metabolise fats, glucose, and carbohydrates.

Always read the label. Follow the directions for use. If symptoms persist, consult your healthcare professional.

Description

UltraFlora Weight & Metabolic Health with Akkermansia is a premium, practitioner-grade formula that features 30 billion pasteurised Akkermansia muciniphila (MucT®) cells, a unique and clinically trialled next‑generation postbiotic.

Akkermansia is a naturally occurring gut microbe that typically makes up 1–4% of the gut microbiota, but its levels decline with excess weight and age. Lower amounts of Akkermansia are linked to higher gut inflammation and reduced gut health. Pasteurised Akkermansia muciniphila (MucT®) supports metabolic and cardiovascular system health and assists in the repair of the gut wall lining.

Scientifically researched Green Tea is included in this formula to help maintain healthy weight and Body Mass Index (BMI), when used in conjunction with a program of reduced intake of dietary calories and increased physical activity. Green Tea is also shown to relieve inflammation and support metabolism of fats and lipids.

The addition of Chromium, together with pasteurised Akkermansia muciniphila (MucT®), assists in the metabolism of glucose, sugar, and carbohydrates. Plus, other key nutrients are included to support energy levels, healthy gastrointestinal immune function and general health and wellbeing.

Clinical Benefits

Pasteurised Akkermansia muciniphila MucT® (hereafter referred to as MucT®) is a next-generation postbiotic selected for its ability to reinforce barrier integrity and translate gut-level signalling into clinically relevant metabolic effects [1–3,9]. This is complemented by green tea polyphenols (including epigallocatechin-3-gallate (EGCG)), chromium, riboflavin and vitamin D3, which extend support across glucose metabolism, insulin responsiveness, and immune–barrier regulation [5,6,10–12]. Together, this formulation positions metabolic care to begin where upstream drivers originate: the gut.

Supports weight maintenance following weight lossMucT®, administered after ≥8% diet-induced weight loss in individuals who were overweight or living with obesity, reduced weight regain and supported weight maintenance versus placebo [1]. In this randomised controlled trial, participants completed an 8-week weight loss phase followed by a 24-week maintenance phase with daily MucT® (30 billion colony-forming units (CFU)) or placebo. The MucT® group experienced significantly less weight regain (p=0.012) and greater net weight loss to week 32 (Figure 1) alongside preserved insulin sensitivity and adipose transcriptomic changes consistent with reduced inflammation and enhanced mitochondrial and oxidative function.

Improves metabolic health: In a randomised, double-blind, placebo-controlled trial in 32 overweight or obese, insulin-resistant adults, 12 weeks of MucT® (10 billion CFU daily) significantly improved multiple metabolic parameters [2]. Insulin sensitivity increased by 28% (Figure 2) and fasting insulin decreased by 34%, alongside a 9% reduction in total cholesterol versus placebo. Plasma lipopolysaccharide (LPS) activity and γ‑glutamyl transferase (GGT) levels were reduced, indicating improvements in barrier integrity and hepatic function. Dipeptidyl peptidase‑IV activity also decreased, suggesting support for inflammatory pathways. White blood cell (WBC) counts, commonly elevated in obesity, were significantly lower in the MucT® group compared with placebo (p=0.037), where levels increased over time. Additionally, serum lactate dehydrogenase (LDH), which has been independently associated with both metabolic syndrome and metabolic dysfunction–associated fatty liver disease (MAFLD), was significantly reduced from baseline (p=0.010) [13]. Favourable trends in body composition were also observed, and the intervention was well tolerated [2].

Ingredients

Key Ingredients

Camelia sinensis (Green tea)

Akkermansia muciniphila MucT® Postbiotic

Active Ingredients

Each tablet contains

Akkermansia muciniphila MucT® Postbiotic 30 billion CFU

Riboflavin 2 mg

Chromium picolinate 201 micrograms

Equivalent Chromium 25 micrograms

Chromium chloride hexahydrate 897 micrograms

Equivalent Chromium 175 micrograms

Total equivalent Chromium 200 micrograms

Colecalciferol (Vitamin D3) Equivalent Vitamin D3 200 IU

Camellia sinensis (Green tea), leaf 409 mg

Derived from dry leaf 12 g

Camellia sinensis (Green tea), leaf Equivalent EGCG 225 mg

Free from: Dairy Protien, Lactose, Eggs, Gluten,Wheat, Nuts, Yeast, Soy Protein, Artificial Colours, Artificial Flavors.

Excipients: Microcrystalline cellulose, Silicon dioxide, Magnesium stearate.

Directions

Take 1 capsule daily prior to exercise with food, or as directed by a healthcare professional. If symptoms persist consult your healthcare professional.

Warnings

Vitamins and mineral supplements should not replace a balanced diet.
Not recommended for use by pregnant and lactating women.
In rare cases, Camellia sinensis may harm the liver. Stop use and see a doctor if you have yellowing skin/eyes, or unusual: fatigue, nausea, appetite loss, abdominal pain, dark urine, or itching.

Storage

Store below 25°C.

Product FAQs

Who is this product for?
UltraFlora Weight & Metabolic Health with Akkermansia is well-suited for adults in midlife who feel that maintaining their weight has gotten harder over time. It is also suitable for adults who have reached their goal weight and want a simple, science-backed daily routine to help maintain their results.

Is this a weight loss product?
UltraFlora Weight & Metabolic Health with Akkermansia is designed to support healthy weight maintenance*,not rapid loss, restriction, or stimulation. For best results, use it in conjunction with a healthy diet and active lifestyle.

Can I take this while I’m on a GLP-1 medication?
UltraFlora Weight & Metabolic Health with Akkermansia may be suitable while on a GLP-1 medication, when transitioning off the medication and throughout the Weight Management journey. As always, consult your healthcare practitioner before starting any new supplement, especially if you’re currently taking medication.

How long until I see results?
In a published clinical study, pasteurised Akkermansia muciniphila (MucT®) was taken daily for 12 weeks and demonstrated improved metabolic health and fat loss. A second clinical study showed that when taken daily for 24 weeks post weight loss, the Akkermansia muciniphila (MucT®) group had gained up to 58% less weight, reducing weight rebound.

How does my gut affect my metabolism?
Your gut is in constant conversation with the rest of your body. Cells lining the gut release natural messengers that help control blood sugar, signal when you’re full, and support how you use energy from food. A healthy gut lining also works as a protective barrier, keeping unwanted substances like bacterial molecules where they belong. When that barrier weakens and your gut bacteria fall out of balance, it can trigger inflammation. Over time, this “low-grade inflammation” may affect how well your body handles blood sugar and fat, which is why gut health and metabolic health are so closely linked.

What is Akkermansia muciniphila and what does it do?
Akkermansia munciniphila is a natural keystone gut bacterium that makes up around 4% of the gut microbiome and declines as you age. High levels of Akkermansia are found in lean, healthy people. Akkermansia is considered a ‘next generation’ biotic and is mentioned in over 5000 research papers. Not all Akkermansia are equal, with the Live (probiotic) forms being unstable and clinical research being conducted on the pasteurised or heat-treated form (postbiotic).

What should I look for in an Akkermansia supplement?
Choosing the best Akkermansia supplement includes consideration of the specific strain used and dosage being backed by human clinical research, as well as meeting strict quality criteria in sourcing and manufacturing. Akkermansiamuciniphila (MucT®)is the original, patented strain based on 20 years of research.

Live vs. Pasteurised Akkermansia – which is better?
In preclinical studies and a proof-of-concept human trial,¹˒² the pasteurised form of Akkermansia muciniphila (MucT®) outperformed the live strain across several measures of metabolic health. It was shown to support a stronger gut barrier, healthy blood sugar response, and healthy body composition and lipid levels. That’s why we’ve built our formula around the pasteurised form: it’s the version the science points to.

Based on preclinical (laboratory and animal) studies and an early-stage human proof-of-concept trial. Individual results may vary.

Does UltraFlora Weight & Metabolic Health with Akkermansia need to be refrigerated?
No, UltraFlora Weight & Metabolic Health with Akkermansia uses pasteurised Akkermansia muciniphila (MucT®) which is a postbiotic. Postbiotics are non-living viable cells and therefore this product is shelf-stable at room temperature and no refrigeration is required.

When should I take this supplement?
Take 1 capsule daily prior to exercise with food. Since UltraFlora Weight & Metabolic Health with Akkermansia contains Green Tea, which is best taken with food to keep things gentle on your stomach. We always recommend speaking to your healthcare practitioner for personalised advice.

Can I take this supplement while pregnant or breastfeeding?
UltraFlora Weight & Metabolic Health with Akkermansia is not recommended for use by pregnant or lactating women. We always recommend speaking to your healthcare practitioner for personalised advice.

Can I give this supplement to my child?
No, UltraFlora Weight & Metabolic Health with Akkermansia is not recommended for children under the age of 18. We always recommend speaking to your healthcare practitioner for personalised advice.